Unique clinical characteristics and SCN5A mutations in patients with Brugada syndrome in Taiwan
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
114
Journal Issue
7
Pages
620-626
Date Issued
2015-07
Author(s)
Chiu, Fu-Chun
Tseng, Chuen-Den
Sherri Yeh, Shih-Fan
Abstract
Brugada syndrome (BrS) is a hereditable sudden cardiac death (SCD). Mutations in the SCN5A gene (the most common BrS-causing gene) are responsible for 20-25% of this disease in Caucasian populations. However, the prevalence of SCN5A mutations in patients with BrS in the Chinese Han population in Taiwan remains unknown. Therefore, in this study, we investigated the prevalence of the SCN5A mutation in the largest BrS cohort in Taiwan.
Subjects
Brugada syndrome; SCN5A mutations; Taiwan; sodium channel
SDGs
Publisher
ELSEVIER TAIWAN
Type
journal article