Electrowetting-on-dielectric (EWOD): Current perspectives and applications in ensuring food safety
Journal
Journal of food and drug analysis
Journal Volume
28
Journal Issue
4
Pages
595
Date Issued
2020-12-15
Author(s)
Barman, Snigdha Roy
Khan, Imran
Chatterjee, Subhodeep
Saha, Subhajit
Choi, Dukhyun
Lee, Sangmin
Abstract
Digital microfluidic (DMF) platforms have contributed immensely to the development of multifunctional lab-on-chip systems for performing complete sets of biological and analytical assays. Electrowetting-on-dielectric (EWOD) technology, due to its outstanding flexibility and integrability, has emerged as a promising candidate for such lab-on-chip applications. Triggered by an electrical stimulus, EWOD devices allow precise manipulation of single droplets along the designed electrode arrays without employing external pumps and valves, thereby enhancing the miniaturization and portability of the system towards transcending important laboratory assays in resource-limited settings. In recent years, the simple fabrication process and reprogrammable architecture of EWOD chips have led to their widespread applications in food safety analysis. Various EWOD devices have been developed for the quantitative monitoring of analytes such as food-borne pathogens, heavy metal ions, vitamins, and antioxidants, which are significant in food samples. In this paper, we reviewed the advances and developments in the design of EWOD systems for performing versatile functions starting from sample preparation to sample detection, enabling rapid and high-throughput food analysis.
Subjects
Digital microfluidics; Electrowetting-on-dielectric; Food safety; Biological assay; Lab-on-a-chip; Microelectromechanical system; POLYMERASE-CHAIN-REACTION; HEAVY-METAL IONS; DIGITAL MICROFLUIDIC CHIP; LOW-COST; RAPID DETECTION; PATHOGEN DETECTION; CHEMICAL CONTAMINANTS; SENSITIVE DETECTION; SAMPLE PREPARATION; LIQUID DROPLET
SDGs
Publisher
DIGITAL COMMONS BEPRESS
Type
review