Steroid refractory interstitial pneumonitis in a patient with juvenile dermatomyositis
Journal
Journal of Microbiology, Immunology and Infection
Journal Volume
35
Journal Issue
4
Pages
259-261
Date Issued
2002
Author(s)
Abstract
Interstitial pneumoni tis is a severe complication of juvenile dermatomyositis. We report a 4-year-old girl with juvenile dermatomyositis. Coughing, shortness of breath, and general malaise developed during steroid treatment. The histology of her lung biopsy is compatible with interstitial pneumonitis. Aggressive treatment including intravenous methylprednisolone pulse therapy, intravenous immunoglobulin, and oral cyclosporin all failed. Creatinine phosphokinase level was within the normal range during the disease course. The clinical features are discussed and the importance of a differential diagnosis of interstitial pneumonitis in patients with juvenile dermatomyositis is emphasized.
SDGs
Other Subjects
amphotericin B; antifungal agent; azathioprine; cyclophosphamide; cyclosporin; immunoglobulin; immunosuppressive agent; methylprednisolone sodium succinate; prednisolone; steroid; article; case report; childhood disease; dermatomyositis; disease course; female; human; interstitial pneumonia; lung aspergillosis; lung biopsy; onset age; preschool child; respiratory failure; steroid therapy; Anti-Inflammatory Agents; Child, Preschool; Cyclosporine; Dermatomyositis; Female; Humans; Lung Diseases, Interstitial; Methylprednisolone; Pulse Therapy, Drug; Treatment Failure
Type
journal article