Aristolochic acid-containing Chinese herbal medicine and upper urinary tract urothelial carcinoma in Taiwan: a narrative review
Journal
World journal of urology
Date Issued
2022-07-22
Author(s)
Abstract
The high incidence of upper urinary tract urothelial carcinoma (UTUC) in Taiwan is largely due to exposure to aristolochic acid (AA), a principal component of Aristolochia-based herbal medicines. Here we systematically review the molecular epidemiology, clinical presentation and biomarkers associated with AA-induced UTUC.
Subjects
Aristolochia; DNA adduct; Mass spectrometry; Nephropathy; Renal pelvic cancer; Ureteral cancer
Publisher
SPRINGER
Type
journal article