Penile tuberculosis associated with monoclonal gammopathy of undetermined significance
Journal
Journal of the Formosan Medical Association
Journal Volume
105
Journal Issue
9
Pages
753-755
Date Issued
2006
Author(s)
Abstract
Mycobacterium tuberculosis (TB) infection of the penis is a rare but serious problem. We report a case of penile TB in a 75-year-old man who presented with fever and dyspnea. No active lung lesions except pleural and pericardial effusion were found on chest X-ray. Monoclonal gammopathy of undetermined significance was diagnosed after serum and urine electrophoresis studies, and repeated bone marrow studies. Genital examination showed diffuse papulonecrotic skin ulcers involving the whole penile shaft, extending ventrally to the median raphe of the scrotum. Pus smear showed positive acid-fast stain, and culture yielded M. tuberculosis. Culture of pleural and pericardial effusion was also positive for M. tuberculosis. Anti-TB treatment was given with isoniazid, ethambutol, rifampin and pyrazinamide, and the cutaneous lesion was noted to be healed at follow-up 6 months later. Although rare, the possibility of TB as a cause of genital ulcer should be kept in mind. ? 2006 Elsevier & Formosan Medical Association.
Subjects
Antibody; Genitourinary; Multiple myeloma; Mycobacterium
SDGs
Other Subjects
ethambutol; isoniazid; pyrazinamide; rifampicin; aged; anamnesis; antibiotic resistance; article; bacterial strain; bacterium culture; case report; clinical feature; dose response; drug dose reduction; dyspnea; electrophoresis; fever; genital system examination; human; hyperuricemia; male; monoclonal immunoglobulinemia; Mycobacterium tuberculosis; nonhuman; penis tuberculosis; pericardial effusion; pleura effusion; retreatment; thorax radiography; treatment duration; treatment outcome; treatment withdrawal; urinalysis; urogenital tuberculosis; visual disorder
Publisher
Scientific Communications International Ltd
Type
journal article