Effect of multivalent cations on the adhesion rate of cellular surfaces bearing ionizable groups
Journal
Colloids and Surfaces A: Physicochemical and Engineering Aspects
Journal Volume
96
Journal Issue
1¤ë2¤é
Pages
155-163
Date Issued
1995
Author(s)
Chang Y.-I.
Abstract
The effect of the presence of multivalent cations in a suspension medium on the rate of adhesion of a charge-regulated cell is investigated theoretically. By using sheep leucocytes as an illustrative example, it is found that the presence of multivalent cations has the effect of decreasing the rate of adhesion of the cells. On the basis of the concept of the Donnan potential, it is found that the magnitude of the electrostatic force for an ion-penetrable membrane is much smaller than that for an ion-impenetrable cell membrane. Under a fixed concentration of cations in the suspension medium, the rate of adhesion of the cells increases with the P?clet number, aspect ratio and Hamaker constant. ? 1995.
Subjects
Adhesion rate
DLVO theory
Multivalent cations
Sheep leucocytes
Type
journal article