Exploration of Fatigue, Depression and Quality of Life in Heart Transplant Recipients
Date Issued
2009
Date
2009
Author(s)
Chou, Yu-Ying
Abstract
The purpose of this study is to explore the symptom distress, fatigue, depression and quality of life in heart transplant recipients, and associated factors of quality of life (QOL). The 108 outpatients who undergone heart transplantation were recruited from the Department of Cardiac Surgery, Nation Taiwan University Hospital, during October 2, 2008 and March 26, 2009. A cross - sectional correlated study was designed. A set of questionnaire with the Transplant Symptom Frequency and Symptom Distress Scale, Hospital Anxiety and Depression Scale (HADS) , Fatigue Symptom Inventory (FSI) , and 12-item Short-Form Health Survey (SF-12) were used to collected symptom distress, fatigue, depression, and QOL . Data were analyzed with SPSS 16.0 software. he main results include: (1) Top five most distressed symptoms were fatigue, orgetfulness, poor vision, muscle weakness, and acne. The symptom frequency and symptom distress are changed as time after heart transplantation; (2) Fatigue intensity is moderate, and fatigue interference is mild. Correlated factors with fatigue intensity were age (rs = -.30, p < .01) , exercise frequency every week (rs = - .24, p < .05) , life interference events (rs = .29, p < .01) , blood urea nitrogen (rs = - .22, p < .05) , medicine receive (rs = -.24, p < .05) , PeakVO2 (rs = .41, p < .01) , symptom distress (rs = .27, p < .01) , and depression (rs = .22, p < .05) . Besides, Life interference events (rs = .32, p< .01) , AST (rs = -.22, p < .05) , blood urea nitrogen (rs = -.26, p < .01) , medicine received (rs = -.19, p < .05) , symptom frequency (rs = .28, p < .01) , symptom distress (rs = .40, p < .01) , and depression (rs = .26, p < .01) were associated with fatigue interference. (3) Correlated factors with depression were employment (t = -3.12, p < .01) , Life interference events (rs = .41, p < .01) , operation period after heart transplantation (rs = .20, p < .05) , physical function (rs = -.32, p < .01) , symptom frequency (rs = .32, p < .01) , symptom distress (rs = .22, p < .05) , fatigue intensity (rs = .22, p < .05) , and fatigue interference (rs = .26, p < .01). (4) Recipients showed the score of PCS was 41.57 and MCS was 47.56, respectively. (5) For physical domain of QOL that the predictors including physical functional status, NYHA classification, life interference events, and the presence of chronic disease before transplantation ; for mental domain of QOL that the predictors including fatigue interference, symptom distress, depression, and NYHA classification. These major factors which may help to identify the potential risk of symptom distress, fatigue, and depression can be further provided to be a reference of rehabilitation-program. Besides, the quality of life also can be improved.
Subjects
Heart Transplantation
Symptom Distress
Fatigue
Depression
Quality of life
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