Innovative Lipid-Based Nanobiotechnology: Diagnostics and Medicine
Journal
ACS nano
Journal Volume
20
Journal Issue
5
Start Page
3944
End Page
3985
ISSN
1936-086X
Date Issued
2026-02-10
Author(s)
Seo, Sung Eun
Kim, Kyung Ho
Singh, Shubham
Chen, Jia-Sin
Iijima, Sumio
Ryu, Yong-Sang
Song, Hyun Seok
Li, Wei-Peng
Kwon, Oh Seok
Abstract
The aim of this review article is to provide a summary of the state-of-the-art technology for the integration of lipid-based natural biomaterials, emphasizing mainly broad applications, especially in therapeutics and diagnostics. Herein, we focused mainly on the utilization of bioengineered lipid-based nanomaterials as medicine and diagnostic agents, which constitute the primary focus of the field of bioengineered lipid-based nanomaterials. Each property of diverse classes of lipid-based nanomaterials is determined by their chemical structure, functionality, and synthesis methodology, and they are versatile for use as drug-delivery nanocarriers, for targeting certain types of cancer cells and for controlled immune therapies. In addition, lipid-based biomaterials have been applied in various research fields with subsequent surface engineering with modulation moieties for the integration of functional nanomaterials (signaling pathway mediators, nucleic acid drugs, and active targeting proteins). The overall manuscript is organized in sections describing materials, fabrication processes, and applications based on innovative lipid-based nanobiotechnology.
Subjects
diagnosis
drug delivery
hybrid bionanomaterials
lipid nanomaterial
nanobiotechnology
nanocarrier
pharmaceutical application
sensing platform
therapeutics
Type
review