Chapter 16 Regulation of Gene Expression in Bacteria and Bactaeriophages
Date Issued
2000
Date
2000
Author(s)
Wang, Yue-Wen
DOI
246246/2006092815540057
Abstract
1. Growth and division genes of bacteria are regulated genes. Their expression is controlled by the needs of the cell as it responds to its environment with the goal of increasing in mass and dividing.
2. Genes that generally are continuously expressed are constitutive genes (housekeeping genes). Examples include protein synthesis and glucose metabolism.
3. All genes are regulated at some level, so that as resources dwindle the cell can respond with a different molecular strategy.
4. Prokaryotic genes are often organized into operons that are cotranscribed. A regulatory protein binds an operator sequence in the DNA adjacent to the gene array, and controls production of the polycis-tronic (polygenic) mRNA.
5. Gene regulation in bacteria and phage is similar in many ways to the emerging information about gene regulation in eukaryotes, including humans. Much remains to be discovered; even in E. coli, one of the most closely studied organisms on earth, 35% of the genomic ORFs have no attributed function.
Publisher
臺北市:國立臺灣大學農藝學系
Type
learning object
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ch16.ppt
Size
2.75 MB
Format
Microsoft Powerpoint
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(MD5):04701ab0f2e32dbc9a63a4f8b83f465a