Modeling the detachment and transport of bubbles from nucleation sites in small vessels
Journal
IEEE Transactions on Biomedical Engineering
Journal Volume
54
Journal Issue
11
Pages
2106-2108
Date Issued
2007
Author(s)
Abstract
Decompression sickness is known to be due to the formation of bubbles in the body as a result of decompression. It is likely that these bubbles form from pre-existing nuclei, which, for bubbles in the bloodstream, are thought to be housed within blood vessel walls. Gas pockets emerging from these sites will be subject to forces due to blood flow, a portion of the gas eventually being swept away to form a free bubble in the bloodstream. These continue to grow and may grow to similar dimensions to the vessel, developing into elongated "gas plugs," potentially occluding the flow. In this correspondence, we derive a simple model to investigate whether this vessel occlusion is a serious concern. ? 2007 IEEE.
Subjects
Blood
Blood vessels
Bubble formation
Flow of fluids
Nucleation
Decompression
Gas pockets
Bubbles (in fluids)
article
blood flow
blood vessel occlusion
cell nucleus membrane
decompression sickness
disease model
Biological Transport, Active
Capillaries
Computer Simulation
Decompression Sickness
Diffusion
Gases
Humans
Models, Cardiovascular
Nitrogen
Regional Blood Flow
Surface Properties
SDGs
Type
journal article