Pyrazinamide related prolonged drug-induced liver injury: A case report
Journal
Medicine
Journal Volume
101
Journal Issue
39
Pages
E30955
Date Issued
2022-09-30
Author(s)
Abstract
Drug induced liver injury (DILI) is a common side effect causing treatment discontinuation during tuberculosis (TB) treatment, and pyrazinamide (PZA) usually leads to a delayed and prolonged abnormal liver function of the 4 standard anti-tuberculosis regimens. However, a prolonged hepatitis lasting more than 4 months is rarely reported.
Subjects
hepatotoxicity; isoniazid; NAT2 polymorphism; pharmacogenetic; pyrazinamide; ANTITUBERCULOSIS DRUGS; LATENT TUBERCULOSIS; SUSCEPTIBILITY; HEPATOTOXICITY; TAIWAN; POLYMORPHISMS; HEPATITIS; RIFAMPIN; THERAPY; NAT2
SDGs
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Type
journal article