An improved oxidative cleavage method for large scale preparation of some acid-labile aglycones from glycosides
Journal
Journal of the Chinese Chemical Society
Journal Volume
49
Journal Issue
1
Pages
103-106
Date Issued
2002
Author(s)
Abstract
Abstract A practical method for large‐scale preparation of acid‐labile aglycones including protopanaxadiol, protopanaxatriol, cycloastragenol, and jujubogenin from the corresponding glycoside containing fraction was developed. The key point of this improved method is to generate and maintain the critical reaction conditions, anhydrous and strongly basic, in situ . This effort over comes the weakness of the reported method for oxidative cleavage of glycones and scales up the preparation of these acid‐labile aglycones for further studies.
SDGs
Type
journal article