Preparation of fluorescent silica nanotubes and their application in gene delivery.
Resource
Adv. Mater.,17,404-407.
Journal
Adv. Mater
Journal Issue
17
Pages
404-407
Date Issued
2005-04
Date
2005-04
Author(s)
Abstract
Fluorescent silica nanotubes are synthesized through a sol–gel reaction using an anodic aluminum oxide membrane template. The nanotubes are filled with plasmid DNA encoding green fluorescence protein (GFP), which are incorporated into mammalian cells that subsequently express GFP (see Figure). The results demonstrate a novel application of nanotubes in biomolecule delivery.