Comparing Low- or Standard-Dose Alteplase in Endovascular Thrombectomy: Insights From a Nationwide Registry
Journal
Stroke
Journal Volume
55
Journal Issue
3
Start Page
532
End Page
540
ISSN
0039-2499
Date Issued
2024-03-01
Author(s)
Hsieh, Yi-Chen
Lin, Chun-Jen
Chen, Yu-Wei
Lin, Kuan-Hung
Sung, Pi-Shan
Tang, Chih-Wei
Chu, Hai-Jui
Tsai, Kun-Chang
Chou, Chao-Liang
Lin, Ching-Huang
Wei, Cheng-Yu
Yen, Shang-Yih
Chen, Po-Lin
Yeh, Hsu-Ling
Chan, Lung
Sung, Sheng-Feng
Lee, Meng
Lee, I-Hui
Lien, Li-Ming
Chiou, Hung-Yi
Lee, Jiunn-Tay
Abstract
Timely intravenous thrombolysis and endovascular thrombectomy are the standard reperfusion treatments for large vessel occlusion stroke. Currently, it is unknown whether a low-dose thrombolytic agent (0.6 mg/kg alteplase) can offer similar efficacy to the standard dose (0.9 mg/kg alteplase).
Subjects
hemorrhage; ischemic stroke; reperfusion; stroke; thrombectomy
SDGs
Type
journal article