The Design and Application of Micro RF Coil
Date Issued
2007
Date
2007
Author(s)
Hsieh, Meng-Chi
DOI
zh-TW
Abstract
Magnetic resonance image (MRI) is a non-invasive imaging system. The two
main streams of technique improvement are decreasing scan time and increasing
spatial resolution. In clinical, temporal resolution is more important than spatial
resolution. But high spatial resolution MR imaging might become powerful tool for
biological studies and other applications. At the present time, there are many
researches have been done to increase the sensitivity of the radiofrequency (RF) coils
to increase signal-to-noise ratio (SNR) with higher spatial and temporal resolution.
Among all, decreasing coil size seems to be the suitable way for magnetic resonance
microscopy (MRM).
In this thesis, we will probe into the effect between high spatial resolution and
the loss of magnetic resonance signal from the basic MR theory. We also simulate the
magnetic field distribution of RF coil by downsizing coil size using numerical
analysis. Instead of conventional quasi-static magnetic field simulation, we construct
a 3D model approached real structure and tune/match to 125.3 MHz/ 50 ohm to obtain
magnetic filed distribution and optimize decouple of micro-fabricated phase array coil.
iii
Then we match up circuit design and transmit-only and receive-only (TORO) mode to
obtain high quality MR image.
Zebrafish is an important model of neuroscience development and optical studies
in zebrafish are restricted to very early developmental stages due to the opacity of the
juvenile and adult stages. In the study, we used non-invasive MRI system obtain two
different kinds of small animal high resolution MR images: zebrafish brain and
hippocampus of rat. Compared with commercial micro volume coil, the SNR and
CNR (contrast-to-noise) can be improved clearly by using our RF coils, about 3~4
times. It can be validated that our RF coils indeed can obtain high quality small
animal magnetic resonance microscope.
Subjects
磁共振顯微影像、射頻線圈、HFSS、斑馬魚腦
magnetic resonance microscope, RF coil, HFSS, zebrafish brain
Type
thesis
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