Recommendations for the treatment and management of adult B-Cell acute lymphoblastic leukemia in Asia-Pacific: Outcomes from a pilot initiative
Journal
Asia-Pacific journal of clinical oncology
Journal Volume
20
Journal Issue
3
Pages
325 - 334
Date Issued
2023-12-26
Author(s)
Lao, Zhentang
Lam, Kwong Yok
Cheung, Yuk Man Carol
Teng, Chieh-Lin
Radhakrishnan, Vivek
Bhurani, Dinesh
Goh, Yeow Tee
Abstract
The outcomes of adult B-cell acute lymphoblastic leukemia (ALL) remain poor. Recent advancements in the field of leukemia research show potential for improved patient care. However, the adoption of research findings into clinical practice is fraught with practice- and country-specific challenges. The continued addition of new findings warrants critical evaluation for the feasibility of incorporation into clinical practice. A uniform set of evidence-based guidelines can favorably assist physicians in making optimal clinical decisions. Such a resource may also serve as a reference point for strategic planning of initiatives aimed at addressing critical barriers in the optimal management of B-cell ALL. This initiative was undertaken to seek a collaborative perspective and understand the existing challenges. Concordance-based recommendations were outlined through a systematic discussion on various aspects of treatment and management of adult B-cell ALL. The outcomes and experiences gained from this exercise will serve as a foundation for future efforts encompassing the more granular aspects of the management of B-cell ALL across the Asia-Pacific region.
Subjects
Asia-Pacific; B-cell ALL; acute lymphoblastic leukemia; consensus; recommendations for B-cell ALL
Type
journal article
review