High 18F-fluorothymidine uptake for invasive thymoma
Journal
Clinical nuclear medicine
Journal Volume
37
Journal Issue
10
Date Issued
2012-01-01
Author(s)
Abstract
We report an invasive thymoma discovered incidentally by an 18F-FLT (fluorothymidine) PET study on a 48-year-old woman. The patient had equivocal breast lesions in her bilateral breasts. She entered a clinical 18F-FLT PET trial in our hospital to differentiate malignant breast tumors from benign ones. No 18F FLT-avid lesions in her breasts were revealed. But an intense 18F-FLT uptake lesion was noted in her right anterior mediastinum. However, an F-FDG PET scan showed only mild F-FDG uptake in the lesion. Video-assisted thoracic surgery thymectomy was subsequently performed, and the final pathology showed invasive thymoma.
SDGs
Other Subjects
2',3' dideoxynucleoside derivative; 3' fluorothymidine; diagnostic agent; article; cancer invasion; case report; female; human; metabolism; middle aged; pathology; positron emission tomography; scintiscanning; thymoma; transport at the cellular level; Biological Transport; Dideoxynucleosides; Female; Humans; Middle Aged; Neoplasm Invasiveness; Positron-Emission Tomography; Thymoma; Thymus Neoplasms
Type
journal article