Clinical feasibility of Gd-EOB-DTPA-enhanced MR imaging for assessing liver function: Validation with ICG tests and parenchymal cell volume
Journal
Clinical Imaging
Journal Volume
40
Journal Issue
4
Pages
797-800
Date Issued
2016
Author(s)
Abstract
Objective: Using Gd-EOB-DTPA-enhanced MRI to assess liver function and validate with indocyanine green (ICG) tests and parenchymal cell volume (PCV). Methods: Nineteen patients scheduled for operation were enrolled. Functional liver volume (FLV) was computed from 20 min post-contrast images. ICG retention was measured in serum 15 min after injection. The histological PCV was determined from resected liver specimen. Results: FLV showed significantly correlated with ICG retention (ICG-R15: r =-0.47, P = .042) and PCV (r = 0.814, P <.001). Conclusions: Gd-EOB-DTPA-enhanced MRI is clinically feasible for quantifying liver function. ? 2016 Elsevier Inc.
SDGs
Other Subjects
Medical imaging; Radiology; Chronic liver disease; Clinical feasibility; Gd-EOB-DTPA; Indocyanine Green; Liver fibrosis; Liver functions; Liver specimens; Parenchymal cells; Magnetic resonance imaging; gadoxetic acid; indocyanine green; contrast medium; gadolinium pentetate; gadoxetic acid; indocyanine green; adult; aged; Article; chronic liver disease; clinical article; contrast enhancement; feasibility study; female; human; human tissue; image analysis; liver cell; liver function; liver histology; liver weight; male; middle aged; Model For End Stage Liver Disease Score; nuclear magnetic resonance imaging; parenchymal cell volume; priority journal; radiological parameters; regional of interest; validation study; cell size; diagnostic imaging; image enhancement; liver; nuclear magnetic resonance imaging; pathology; pathophysiology; procedures; reproducibility; Adult; Aged; Cell Size; Contrast Media; Feasibility Studies; Female; Gadolinium DTPA; Humans; Image Enhancement; Indocyanine Green; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Reproducibility of Results
Type
journal article