Increased risk of prostate cancer following sexually transmitted infection in an Asian population
Resource
Epidemiol. Infect., 141(12), 2663-2670
Journal
Epidemiology and Infection
Pages
2663-2670
Date Issued
2013
Date
2013
Author(s)
Chung, S. D.
Lin, Y. K.
Huang, C. C.
Lin, H. C.
Abstract
The relationship between sexually transmitted infections (STIs) and prostate cancer (PC) remains inconclusive. Moreover, all such studies to date have been conducted in Western populations. This study aimed to investigate the risk of PC following STI using a population-based matched-cohort design in Taiwan. The study cohort comprised 1055 patients with STIs, and 10 550 randomly selected subjects were used as a comparison cohort. Cox proportional hazards regression analysis revealed that the hazard ratio for PC during the 5-year follow-up period for patients with a STI was 1.95 (95% confidence interval 1.18-3.23), that of comparison subjects after adjusting for urbanization level, geographical region, monthly income, hypertension, diabetes, hyperlipidaemia, obesity, chronic prostatitis, history of vasectomy, tobacco use disorder, and alcohol abuse. We concluded that the risk of PC was higher for men who were diagnosed with a STI in an Asian population.
Subjects
Prostate cancer
sexually transmitted infections
SDGs
Other Subjects
adult; aged; alcohol abuse; Article; Asian; cancer risk; chronic prostatitis; cohort analysis; comorbidity; controlled study; diabetes mellitus; geographic distribution; human; hyperlipidemia; hypertension; income; major clinical study; male; obesity; patient history of male sterilization; patient history of vasectomy; population research; prostate cancer; risk assessment; sexually transmitted disease; Taiwan; tobacco use; urbanization