MicroRNA-mediated surveillance of phosphate transporters on the move
Journal
Trends in Plant Science
Journal Volume
19
Journal Issue
10
Pages
647-655
Date Issued
2014
Author(s)
Abstract
Phosphate (Pi), which is indispensable for the structural and metabolic needs of plants, is acquired and translocated by Pi transporters. Deciphering the regulatory network of Pi signaling and homeostasis that involves the control of Pi transporters trafficking to, and their activity at, the plasma membrane provides insight into how plants adapt to environmental changes in Pi availability. Here, we review recent studies that revealed the involvement of microRNA399-PHOSPHATE 2 (PHO2) and microR827-NITROGEN LIMITATION ADAPTATION (NLA) modules in mediating the ubiquitination and degradation of PHOSPHATE TRANSPORTER 1 (PHT1) and/or PHOSPHATE 1 (PHO1). These discoveries show that miRNAs are an effective way for plants to monitor the turnover of Pi transporters in the membrane system by modulating the functioning of the membrane-associated ubiquitin machinery. © 2014 Elsevier Ltd.
Other Subjects
microRNA; phosphate; phosphate transporter; plant RNA; vegetable protein
adaptation; biological model; cell membrane; gene expression regulation; genetics; homeostasis; metabolism; phenotype; plant; signal transduction; transport at the cellular level
Type
journal article