Genome-wide DNA hypermethylation and homocysteine increase a risk for myopia
Journal
International Journal of Ophthalmology
Journal Volume
12
Journal Issue
1
Pages
38 - 45
Date Issued
2019
Author(s)
Abstract
AIM: To test for the association between genome-wide methylation and myopia in human and mice. METHODS: methylation levels. RESULTS: methylation and DNA methyltransferase levels. CONCLUSION: hypermethylation may be associated with high myopia in human and mice. Homocysteine and methionine are accumulated in myopic eyes, which may provide excess methyl group for genome-wide methylation.
SDGs
Type
journal article