A Survey on the Prevalence of Hepatocellular Carcinoma and Hepatitis B Virus Infection in Peng-Hu, Taiwan
Other Title
澎湖地區肝細胞癌及B型肝炎之盛行率調查
Journal
Chinese journal of gastroenterology
Journal Volume
5
Journal Issue
2
Pages
57
Date Issued
1988-06-01
Author(s)
Jaw-Town Lin
Ming-Yang Lai
Ding-Shinn Chen
Teh-Hong Wang
Juei-Low Sung
Abstract
Totally 1265 (610 males, 655 females) asymptomatic subjects received abdominal ultrasonography (US) and determination of α-fetoprotein (AFP), and hepatitis B markers at Peng-Hu islands between August 26 and September 2, 1985. The positive rate of hepatitis B surface antigen (HBsAg) was 20.4%, and 9.0% of the population studied were negative for HBsAg, hepatitis B surface antibody (anti-HBs), and hepatitis B core antibody (anti-HBc). The seronegative rate decreased as the age increased. Analyzing the subjects over 40 years old only, the HBsAg Positive rate was 18.4% with 22.4% in males and 14.5% in females. The difference of HBsAg positive rate by sex is statistically significant.
Five subjects with elevated AFP were found. Two were diagnosed as hepatocellular carcinoma (HCC), and 1 decompensated liver cirrhosis. Another six subjects were found to have space occupying lesion by US, none of them was diagnosed as HCC. In total, HCC were found in 2 cases during this survey, AFP increased over 400 ng/ml in 1, increased slightly in 1 and HBsAg was positive in 1 case.
The prevalence of HBV infection in Peng-Hu islands is similar to that in other areas of Taiwan. But in the subjects with HCC detected in this survey, the HBsAg-positive rate seemed lower than those of our previous study. Although the present series is small, we conclude that although combination of abdominal US and AFP is better, AFP is convenient and economic.
Subjects
肝細胞癌
B型肝炎
盛行率調查
hepatocellular carcinoma
hepatitis B
prevalence by mass survey
SDGs
Publisher
中華民國消化系醫學會雜誌
Type
journal article