OVERWEIGHT AND OBESITY-RELATED METABOLIC DISORDERS IN HOSPITAL EMPLOYEES
Resource
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION v.105 n.1 pp.56-63
Journal
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
Journal Volume
v.105
Journal Issue
n.1
Pages
56-63
Date Issued
2006
Date
2006
Author(s)
HUANG, LEE-CHING
TSAI, CHENG-HO
CHEN, TONY, HSIU-HIS
Abstract
Background: Obesity is associated with metabolic disorders and cardiovascular diseases. This study investigated the relationship between overweight and obese status and the incidence of type 2 diabetes, hypertension, hyperlipidemia and hyperuricemia. Methods: This prospective cohort study comprised 1749 hospital employees who received baseline health check-ups in 1993. Data from the 1027 participants ( 832 women, 195 men; mean age, 36 +/- 7 years) who repeated check-ups in 2003 were used in the analysis. Relative risks (RRs) for development of metabolic disorders during follow- up associated with different body mass index (BMI) categories at baseline as defined by Asia-Pacific recommendations and the Department of Health in Taiwan were calculated after adjustment for covariates. Results: The prevalence of overweight and obesity at baseline check-up were 17.6% and 14.5%, respectively. Obese subjects with baseline BMI >= 25 kg/m(2) had a significant multivariate- adjusted RR of 2.7 for hypertension, 14.8 for type 2 diabetes, 3.2 for hyper-triglyceridemia, and 2.8 for hyperuricemia, compared to subjects with baseline BMI < 23.0 kg/m(2). RR for diabetes was higher in women than in men, but RR for hypertriglyceridemia was higher in men. The risks of hypertension and hyperuricemia significantly increased for subjects with baseline BMI >= 23 kg/m(2) while RRs for type 2 diabetes increased significantly for baseline BMI >= 24 kg/m(2) and hypertriglyceridemia increased for baseline BMI >= 25 kg/m(2). The risks attributable to obesity ( baseline BMI >= 25 kg/m(2)) were 23.0% for hypertension, 70. 8% for diabetes, 27.9% for hypertriglyceridemia, and 24.1% for hyper-uricemia. Conclusion: This study revealed that a high prevalence of over-weight and obesity was associated with significantly increased risk of development of type 2 diabetes, hypertension, hypertriglyceridemia and hyperuricemia in hospital employees, suggesting the need for programs to improve weight management.
Subjects
body mass index
hypercholesterolemia
hypertension
hypertriglyceridemia
hyperuricemia
type 2 diabetes
SDGs
Type
journal article