Amino acid sequence of pelamitoxin a, the main neurotoxin of the sea snake, Pelamis platurus
Journal
Toxicon
Journal Volume
14
Journal Issue
6
Pages
459-466
Date Issued
1976
Author(s)
Abstract
The amino acid sequence of pelamitoxin a, the main neurotoxin of the sea snake, Pelamis platurus, has been completed. Analysis was done principally by means of Edman degradation of constituent tryptic peptides; chymotryptic and thermolytic peptides were also studied to assist in the sequence alignment. The results indicate that pelamitoxin a is identical to schistosa toxin 5 in amino acid sequence. These results indicate the feasibility of producing a common antivenin against toxins from some of the most common sea snakes. © 1976.
SDGs
Type
journal article