Antibiotic therapy for Listeria monocytogenes bacteremia
Journal
Journal of the Formosan Medical Association
Journal Volume
94
Journal Issue
1-2
Pages
19-22
Date Issued
1995
Author(s)
Abstract
Listeria monocytogenes has been recognized as an important pathogen in immunocompromised patients, but it has been rarely reported in Taiwan. We reviewed 13 cases of L. monocytogenes bacteremia at National Taiwan University Hospital over a 12-year period. All of the patients had underlying diseases. Fever was the most common presenting symptom, and neurologic signs were found in 6 patients. Most of the patients received penicillin G, ampicillin or piperacillin with an aminoglycoside. Corticosteroids were used in 9 of 13 patients. The overall mortality directly due to L. monocytogenes bacteremia was 31%. However, patients treated with cephalosporins or oxacillin had higher mortality than those treated with penicillin G, ampicillin or piperacillin (p = 0.05). Given the increasing number of immunosuppressed patients in Taiwan, it is likely that more cases will be encountered. Physicians in Taiwan should be aware of L. monocytogenes bacteremia and its treatment.
SDGs
Other Subjects
amikacin; aminoglycoside antibiotic agent; ampicillin; antibiotic agent; cefamandole; cefazolin; cefmetazole; cefotaxime; ceftriaxone; cefuroxime; corticosteroid; netilmicin; penicillin g; piperacillin; tobramycin; adult; aged; article; bacteremia; clinical article; clinical trial; female; fever; human; immune deficiency; listeria monocytogenes; male; newborn; Adolescent; Adult; Aged; Bacteremia; Child, Preschool; Female; Human; Infant, Newborn; Listeria Infections; Listeria monocytogenes; Male; Middle Age; Penicillins; Prognosis
Type
journal article