Recombinant factor VIIa use in refractory ulcer bleeding in uremic patient
Journal
American Journal of Emergency Medicine
Journal Volume
30
Journal Issue
7
Pages
1319.e1-1319.e4
Date Issued
2012
Author(s)
Abstract
Peptic ulcer bleeding is thought to be a major cause of bleeding in patients with end-stage renal disease and is more complicated in uremic patients. We described a 41-year-old man with end-stage renal disease who underwent hemodialysis with refractory ulcer bleeding, failure to all traditional peptic ulcer treatments, and correction of uremic component, who has been successfully treated by using recombinant factor VIIa. There have been few case reports in dealing refractory upper gastrointestinal bleeding in uremic patients in the literature; and in this case report, we demonstrates that recombinant factor VIIa could be used as a rescue therapy in these highsurgical risk patients when medical therapy fails. ? 2012 Elsevier Inc. All rights reserved.
SDGs
Other Subjects
adrenalin; enbucrilate; heparin; proton pump inhibitor; recombinant blood clotting factor 7a; abdominal pain; adult; aorta dissecting aneurysm; argon plasma coagulation; article; artificial embolism; case report; clip; computer assisted tomography; duodenal ulcer bleeding; duodenostomy; embolectomy; femorofemoral bypass; gastrointestinal endoscopy; gastrointestinal hemorrhage; hemodialysis; human; hypertension; hypovolemic shock; kidney failure; laparotomy; male; peptic ulcer bleeding; priority journal; renal replacement therapy; suturing method; transarterial angiographic embolization; treatment failure; uremia; vomiting
Type
journal article