Smart polymers for cell therapy and precision medicine
Journal
Journal of Biomedical Science
Journal Volume
26
Journal Issue
1
Pages
73
Date Issued
2019
Author(s)
Abstract
Soft materials have been developed very rapidly in the biomedical field over the past 10 years because of advances in medical devices, cell therapy, and 3D printing for precision medicine. Smart polymers are one category of soft materials that respond to environmental changes. One typical example is the thermally-responsive polymers, which are widely used as cell carriers and in 3D printing. Self-healing polymers are one type of smart polymers that have the capacity to recover the structure after repeated damages and are often injectable through needles. Shape memory polymers are another type with the ability to memorize their original shape. These smart polymers can be used as cell/drug/protein carriers. Their injectability and shape memory performance allow them to be applied in bioprinting, minimally invasive surgery, and precision medicine. This review will describe the general materials design, characterization, as well as the current progresses and challenges of these smart polymers. ? 2019 The Author(s).
Subjects
Bioprinting; Cell therapy; Precision medicine; Smart materials; Tissue engineering
SDGs
Other Subjects
drug carrier; macrogol; poloxamer; poly(n isopropylacrylamide); polymer; polyurethan; biocompatibility; biodegradability; bioprinting; cell therapy; controlled drug release; covalent bond; human; hydrogel; minimally invasive surgery; personalized medicine; priority journal; Review; stem cell transplantation; three dimensional printing; tissue engineering; tissue regeneration; biological therapy; devices; drug therapy; personalized medicine; procedures; Bioprinting; Cell- and Tissue-Based Therapy; Humans; Precision Medicine; Stimuli Responsive Polymers; Tissue Engineering
Type
journal article