Prediction of Unilateral Meniere's Disease Attack Using Inner Ear Test Battery
Journal
Ear and Hearing
Journal Volume
41
Journal Issue
3
Pages
615
Date Issued
2020-01-01
Author(s)
Wu, Po Hsuan
Lo, Wu Chia
Wang, Chi Te
Wen, Ming Hsun
Huang, Tsung Wei
Cheng, Po Wen
Abstract
Objectives: In the clinical setting, a variety of inner ear test results are obtained from patients with unilateral Meniere's disease (MD). In this study, the authors use inner ear test results as parameters to illustrate the relationship between inner ear function and vertigo attack frequency. Design: We retrospectively enrolled 50 unilateral MD patients. In addition to clinical symptoms, the results of pure-tone audiometry and caloric, acoustic cervical vestibular-evoked myogenic potential (cVEMP), galvanic cVEMP, vibratory ocular VEMP (oVEMP), and galvanic oVEMP tests were collected via chart review. The multiple linear regression method was used to examine which independent variables have a statistically significant influence on vertigo attacks. Results: In affected ears, the abnormal rate of the caloric, acoustic cVEMP, galvanic cVEMP, vibratory oVEMP, and galvanic oVEMP tests was 74%, 76%, 48%, 34%, and 30%, respectively. According to the regression model, the abnormal galvanic cVEMP response and abnormal galvanic oVEMP response had significantly negative correlations with the frequency of vertigo attacks after logarithmic transformation. A predictive model for disease attack frequency using significant parameters and their regression coefficients was proposed: Conclusions: Using the proposed model with galvanic VEMP, clinicians could develop better strategies to manage vertigo attacks in patients with MD.
Subjects
Galvanic cervical vestibular-evoked myogenic potential | Galvanic ocular vestibular-evoked myogenic potential | Meniere's disease | Vertigo attack frequency
SDGs
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Type
journal article