Generation of Transgenic Mice Harboring Human Pulmonary Surfactant-related Protein B/C Genes
Date Issued
2010
Date
2010
Author(s)
Ma, Yun-Yi
Abstract
74
英文摘要
Generation of Transgenic Mice Harboring Human
Pulmonary Surfactant-related Protein B/C Genes
Yun-Yi Ma
Abstract
The purpose of this study was to investigate the effect of advanced culture to
two-cell stage prior to co-injected mouse eggs on pups born and transgene integration
efficiency by pronuclear gene microinjection. Transgenes were constructed by using a
mature surfactant protein B (mSP-B) and C (mSP-C) cDNA fragment equipped with
bovine
英文摘要
Generation of Transgenic Mice Harboring Human
Pulmonary Surfactant-related Protein B/C Genes
Yun-Yi Ma
Abstract
The purpose of this study was to investigate the effect of advanced culture to
two-cell stage prior to co-injected mouse eggs on pups born and transgene integration
efficiency by pronuclear gene microinjection. Transgenes were constructed by using a
mature surfactant protein B (mSP-B) and C (mSP-C) cDNA fragment equipped with
bovine
Subjects
microinjection
transgenic mice
surfactant protein B
surfactant protein C
milk
Type
thesis
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