UNDIAGNOSED DIABETES MELLITUS IN TAIWANESE SUBJECTS WITH IMPAIRED FASTING GLYCEMIA: IMPACT OF FEMALE SEX, CENTRAL OBESITY, AND SHORT STATURE
Resource
CHINESE JOURNAL OF PHYSIOLOGY v.44 n.1 pp.44-51
Journal
CHINESE JOURNAL OF PHYSIOLOGY
Journal Volume
v.44
Journal Issue
n.1
Pages
44-51
Date Issued
2001
Date
2001
Author(s)
PAN, WEN-HAM
YEH, WEN-TING
HWU, CHII-MIN
HO, LO-TONE
Abstract
AIMS - To study the extent and determinants of undiagnosed
diabetes mellitus (DM) in Taiwanese subjects with impaired
fasting glycemia (IFG) defined by the newly proposed WHO
criteria. METHODS - Oral glucose tolerance tests were
carried out for 306 IFG subjects identified from 6632 adult
participants of two large scale community-based studies:
Nutrition and Health Survey in Taiwan (1993-1996) and the
Cardiovascular Disease Two-township Study (1994-1997),
Similar protocols mere used in these two studies to collect
data on glycemic status, anthropometric measurements, and
other data used in the present study. RESULTS - Subjects
with IFG had a non-trivial undiagnosed diabetes mellitus
rate (304 in men and 42% in women) and a high rate of
glucose intolerance and undiagnosed DM combined (75 % in men
and 86 % in women), Women with IFG had a 1.6 fold higher
risk (p = 0.04) for undiagnosed DM and a 2.1 fold higher
risk (p = 0.01) for glucose intolerance and DM when compared
to men. There were more women than men with an elevated
body mass index in undiagnosed DM patients. Among IFG
subjects, undiagnosed DM patients were significantly (p < 0.
05) older, more centrally obese and shorter than their
normal IFG counterparts, irrespective of gender. In men,
height was independent of age and waist circumference in
predicting undiagnosed DM (p = 0.037), CONCLUSIONS - A high
proportion of impaired glucose tolerance and undiagnosed DM
was found in subjects with IFG. Its public health impact
should not be overlooked. Central obesity, female sex, and
short stature mere associated with undiagnosed DM status in
IFG subjects.
Subjects
undiagnosed diabetes mellitus
impaired fasting glycemia
women
central obesity
height
SDGs
Type
journal article