An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles
Journal
Gut
Pages
329701
Date Issued
2023-07-18
Author(s)
Bresalier, Robert S
Senore, Carlo
Young, Graeme P
Allison, James
Benamouzig, Robert
Benton, Sally
Bossuyt, Patrick M M
Caro, Luis
Carvalho, Beatriz
Coupé, Veerle M H
de Klaver, Willemijn
de Klerk, Clasine Maria
Dekker, Evelien
Dolwani, Sunil
Fraser, Callum G
Grady, William
Guittet, Lydia
Gupta, Samir
Halloran, Stephen P
Haug, Ulrike
Hoff, Geir
Itzkowitz, Steven
Kortlever, Tim
Koulaouzidis, Anastasios
Ladabaum, Uri
Lauby-Secretan, Beatrice
Leja, Mārcis
Levin, Bernard
Levin, Theodore Robert
Macrae, Finlay
Meijer, Gerrit A
Melson, Joshua
O'Morain, Colm
Parry, Susan
Rabeneck, Linda
Ransohoff, David F
Sáenz, Roque
Saito, Hiroshi
Sanduleanu-Dascalescu, Silvia
Schoen, Robert E
Selby, Kevin
Singh, Harminder
Steele, Robert J C
Sung, Joseph J Y
Symonds, Erin Leigh
Winawer, Sidney J
Abstract
New screening tests for colorectal cancer (CRC) are rapidly emerging. Conducting trials with mortality reduction as the end point supporting their adoption is challenging. We re-examined the principles underlying evaluation of new non-invasive tests in view of technological developments and identification of new biomarkers.
Subjects
colorectal adenomas; colorectal cancer; colorectal cancer screening
Type
journal article