Mechanisms of Azole Resistance and Trailing in Candida tropicalis Bloodstream Isolates
Journal
Journal of fungi (Basel, Switzerland)
Journal Volume
7
Journal Issue
8
Date Issued
2021-07-28
Abstract
Azole-resistant Candida tropicalis has emerged in Asia in the context of its trailing nature, defined by residual growth above minimum inhibitory concentrations (MICs). However, limited investigations in C. tropicalis have focused on the difference of genotypes and molecular mechanisms between these two traits.
Subjects
efflux pump; ergosterol; fluconazole; isavuconazole; multilocus sequence typing; voriconazole
Type
journal article