Geographic characteristics of HTLV-1 molecular subgroups and genetic substitutions in East Asia: Insights from complete genome sequencing of HTLV-1 strains isolated in Taiwan and Japan
Journal
PLoS neglected tropical diseases
Journal Volume
18
Journal Issue
2
Date Issued
2024-02
Author(s)
Nozuma, Satoshi
Yoshimura, Akiko
Pai, Shun-Chung
Chen, Hung-Jen
Matsuura, Eiji
Tanaka, Masakazu
Kodama, Daisuke
Dozono, Mika
Matsuzaki, Toshio
Takashima, Hiroshi
Kubota, Ryuji
Abstract
Although Japan is a major endemic area for human T-lymphotropic virus type 1 (HTLV-1) and the virus has been well-studied in this region, there is limited research on HTLV-1 in surrounding regions. In this study, we determined the complete genome sequences of HTLV-1 strains isolated from Taiwan and Japan and investigated the geographic characteristics of molecular subgroups and substitution mutations to understand the spread of HTLV-1 and its correlation with human migration.
SDGs
Type
journal article