Expression of osteopontin gene in patients with tuberculous pleurisy and miliary tuberculosis
Date Issued
2005-07-31
Date
2005-07-31
Author(s)
���R�R
DOI
932314B002221
Abstract
Osteopontin, a noncollagenous matrix protein
produced by macrophages and T lymphocytes,
is expressed in granulomatous lesions caused
byMycobacterium tuberculosis infection.
Circulating osteopontin levels have been
found to be elevated in patients with
pulmonary tuberculosis, and correlate with
severity of pulmonary tuberculosis. In the
present study we investigated plasma
osteopontin levels in patients with
tuberculous pleurisy, those with miliary
tuberculosis, as there was no reports of such
study, and compared them with those of
normal control subjects. We found that
plasma osteopontin levels, as measured by an
ELISA assay, were significantly higher in
patients with tuberculous pleurisy, those with
miliary tuberculosis, than in healthy control
subjects.
Subjects
Mycobacterium tuberculosis
pleurisy
miliary
granuloma
SDGs
Publisher
臺北市：國立臺灣大學醫學院檢驗醫學科
Type
journal article
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