Time trends of endoscopic and pathological diagnoses related to gastroesophageal reflux disease in a Chinese population: Eight years single institution experience
Journal
Diseases of the Esophagus
Journal Volume
23
Journal Issue
3
Pages
201-207
Date Issued
2010
Author(s)
Abstract
The discrepancy between Eastern and Western countries exists regarding the time trends of Barrett's esophagus (BE)/adenocarcinoma. We aimed to elucidate this issue through a retrospective review of the endoscopic and pathological diagnoses of gastroesophageal reflux disease (GERD) over time in a Chinese population. All records were analyzed from 2000 to 2007. Records included demographic data, clinical indication for endoscopy, and endoscopic findings. The total number of endoscopic procedures increased over time. The indications for referral endoscopy secondary to GERD increased from 366 cases (4.9%) in the beginning of the study to 1439 cases (14.1%) at the end. Concomitant GERD symptoms did not significantly change (range, 13-15.1%) in screening endoscopic studies. Endoscopic detection of erosive esophagitis increased in referral populations from 1546 (20.7%) to 5207 cases (51%) and by screening endoscopy from 791 (14.5%) to 1983 cases (23.5%). The prevalence of nonerosive reflux disease and BE did not change over time. BE-associated dysplasia and adenocarcinoma were rare. The detection of Los Angeles class A disease increased with time in referral endoscopy cases with a focus on erosive esophagitis composition. The endoscopic demand for GERD investigation and the GERD endoscopic diagnosis increased in our population. The results were related to a higher prevalence of low-grade erosive disease diagnosed. The incidence of BE-associated dysplasia and adenocarcinoma has been the same and the increased screening did not detect more cancers. ? 2009 Copyright the Authors, Journal compilation ? 2010, Wiley Periodicals, Inc. and the International Society for Diseases of the Esopha.
SDGs
Other Subjects
adult; article; Barrett esophagus; Chinese; esophageal adenocarcinoma; esophagus dysplasia; female; gastroesophageal reflux; gastrointestinal endoscopy; gastrointestinal symptom; human; major clinical study; male; patient referral; prevalence; priority journal; reflux esophagitis; screening test; time; adenocarcinoma; aged; Asian; Barrett esophagus; China; cohort analysis; endoscopy; esophagus tumor; ethnology; gastroesophageal reflux; incidence; middle aged; pathology; reflux esophagitis; retrospective study; risk factor; statistics; Adenocarcinoma; Adult; Aged; Asian Continental Ancestry Group; Barrett Esophagus; China; Cohort Studies; Endoscopy; Esophageal Neoplasms; Esophagitis, Peptic; Female; Gastroesophageal Reflux; Humans; Incidence; Male; Middle Aged; Retrospective Studies; Risk Factors
Type
journal article