Interactive 3D hybrid PET/CT imaging in the identification of myocardial viability in patients after myocardial infarction: Feasibility study and clinical implications
Journal
Journal of the Formosan Medical Association
Journal Volume
107
Journal Issue
6
Pages
470-477
Date Issued
2008
Author(s)
Abstract
Background/Purpose: Clinical decision-making in coronary artery disease requires integrated information on myocardial viability and coronary arteries, and cross-modality registration could facilitate this process. The recent emergence of hybrid positron emission tomography (PET)/ computed tomography (CT) allows acquisition of this information in one study session; however, clinically useful software capable of presenting three-dimensional (3D) fused images to assess the relationship between myocardium and coronary arteries is limited. Methods: Patients with prior myocardial infarction were examined using electrocardiographically gated 18F-fluorodeoxyglucose PET and 16-slice CT. Results: There were seven patients; mean age was 59 ± 15 years and six were male. Using 3D reconstruction, coregistration and interactive display, the topographical relationship between myocardial viability and coronary arteries was clearly identified. Conclusion: We present a protocol to acquire CT coronary angiography and PET data and to visualize 3D fused images with an interactive visualization interface. This image coregistration is potentially useful to facilitate the process of image interpretation and decision-making. ?2008 Elsevier & Formosan Medical Association.
Other Subjects
dipyridamole; fluorodeoxyglucose f 18; insulin; iopromide; thallium 201; acute heart infarction; adult; aged; article; clinical article; clinical decision making; computed tomographic angiography; computer assisted tomography; controlled study; coronary artery; diabetes mellitus; electrocardiography; feasibility study; female; heart muscle; human; image analysis; image display; image processing; image reconstruction; in-stent restenosis; male; percutaneous transluminal angioplasty; positron emission tomography; single photon emission computer tomography; three dimensional imaging; two dimensional echocardiography
Publisher
Scientific Communications International Ltd
Type
journal article