行政院國家科學委員會專題研究計畫期中進度報告:以NF-kB 抑制劑及抗凝血蛇毒蛋白抑制眼球之新生血管形成(2/3)
Date Issued
2003
Date
2003
Author(s)
Yang, Chang-Hao
DOI
912314B002201
Abstract
Retinal angiogenesis occurs in a variety of disease, such as proliferative diabetic retinopathy, retinopathy of
prematurity, and uveitis. A αvβ3 integrin dependent vascular endothelial cell migration and proliferation may play
an important role in the pathogenesis of new vessel formation. Disintegrin, a group of RGD-containing peptides
from viper venom, is a strong antagonist of αvβ3 integrin. In this study, the inhibitory effect of disintegrin on
angiogenesis was evaluated in vitro by a bovine retinal capillary endothelial (BRCE) cell culture model.
SDGs
Publisher
臺北市：國立臺灣大學醫學院眼科
Type
journal article
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