Acute pancreatitis in children with acute lymphoblastic leukemia correlates with L-asparaginase dose intensity
Journal
Pediatric research
Date Issued
2021-10-30
Author(s)
Chen, Chi-Bo
Lin, Dong-Tsamn
Chang, Mei-Hwei
Abstract
L-Asparaginase (L-Asp) is an important therapeutic for childhood acute lymphoblastic leukemia (ALL). Asparaginase-associated pancreatitis (AAP) is a severe complication of L-Asp related to the dosage. We investigated the incidence of, and risk factors for, AAP in pediatric patients with ALL.
Subjects
COLI; PHARMACOKINETICS; TOXICITY; ADULTS
Publisher
SPRINGERNATURE
Type
journal article