麻醉深度之最佳化控制(II)
Date Issued
2000-07-31
Date
2000-07-31
Author(s)
DOI
892213E002036
Abstract
It is important in Taiwan to reduce the
risk of anesthetic failure. Therefore, in this
project an automatic system was
implemented for monitoring and control of
anesthetic level. A Windows-based graphic
user interface was developed in this system to
control the infusion pump for drug delivery
in addition to measure the blood pressure (BP)
and EEG of the rat. The results from more
than 30 rats show that the BP decreases as
the depth of anesthesia increases.
Furthermore, the time interval for a rat from
lightly to deeply anesthetized and finally to
death increases exponentially with the body
weight of the rat. In contrast, it decreases
dramatically as the concentration of the
anesthetic agent, here sodium pentobarbital,
increases. The depth of anesthesia is
sensitively reflected by the number of spikes
in the EEG waveform. The deeper the
anesthesia the fewer the sipkes in EEG. It is
suggested that the EEG may be an adequate
index for the monitoring of anesthetic level.
Subjects
EEG
blood pressure
anesthesia
Publisher
臺北市：國立臺灣大學醫學工程學研究所
Type
report
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