Concomitant graves hyperthyroidism with thyrotrophin-secreting pituitary adenoma
Journal
Southern Medical Journal
Journal Volume
103
Journal Issue
4
Pages
347-349
Date Issued
2010
Author(s)
Lee M.-T.
Abstract
The relationship of autoimmune thyroid disease and TSH-producing pituitary tumor is rarely found. We report two patients with hyperthyroidism, a 27-year-old man and a 28-year-old woman, who were diagnosed with Graves hyperthyroidism with elevated free thyroxine (FT4), suppressed TSH and positive thyrotropin receptor autoantibodies. After treatment with antithyroid drugs, FT4 did not return to normal, and serum TSH levels were found to be above-normal range. Pituitary tumors were subsequently found via pituitary magnetic resonance imaging (MRI). We suggest that Graves hyperthyroidism concomitant with TSH-producing pituitary tumor be kept in mind, as it may confuse the therapeutic course of hyperthyroidism and make it more complicated. Copyright ? 2010 by The Southern Medical Association.
SDGs
Other Subjects
autoantibody; carbimazole; microsome antibody; propylthiouracil; thyrotropin; thyrotropin receptor antibody; thyroxine; adult; article; case report; endocrine surgery; female; free thyroxine index; Graves disease; hand tremor; heart palpitation; human; male; nuclear magnetic resonance imaging; thyroid function test; thyrotropin blood level; thyrotropin secreting adenoma; Adult; Female; Graves Disease; Humans; Magnetic Resonance Imaging; Male; Pituitary Neoplasms; Thyrotropin
Type
journal article