Clinical-histopathological features and cancer gene analysis of cutaneous epithelioid angiosarcoma: A report of 4 cases
Journal
JAAD Case Reports
Journal Volume
46
Start Page
45-48
ISSN
2352-5126
Date Issued
2024-04
Author(s)
Tokuchi, Keiko
Yanagi, Teruki
Kurosawa, Suguru
Kitamura, Shinya
Maeda, Takuya
Miyamoto, Kodai
Nishihara, Hiroshi
Ujiie, Hideyuki
Abstract
Angiosarcoma (AS) is a rare variant of malignant soft tissue sarcoma, representing less than 1% of all soft tissue sarcomas.1 Among the histopathological subtypes of AS, epithelioid angiosarcoma (EAS) is characterized by epithelioid morphology, with polygonal or spherical cells containing eosinophilic cytoplasm.2 Tumors where over 80% of the cells are epithelioid are typically classified as EAS.3 EAS usually manifests during adulthood, particularly around the seventh decade of life.2 Approximately 12% of cutaneous AS is cutaneous EAS, yet detailed studies on clinical presentations are lacking.
Subjects
cancer genome analysis
epithelioid angiosarcoma
nodule
plaque
purpura
SDGs
Publisher
Elsevier BV
Type
journal article