A Study of the Correlation of Pulse Wave Transit Time and Heart Rate Variability during Anesthesia
Date Issued
2010
Date
2010
Author(s)
Liu, Wei
Abstract
In an operation room, anesthetics plays an important role and are indispensable. Furthermore, the dosage of anesthetic given is much more important because it may have terrible influences on the patients if it’s not accurate. Generally, general anesthesia affect the patients'' cardiovascular system by cutting off the autonomic nervous system, which causes the patients'' rhythm of the heart and blood vessels'' elasticity to change, weakens the strength of systole, makes the peripheral vascular to extend and so on. These changes of hemodynamic may cause the patients'' blood pressure to drop and will probably result in shock. Moreover, those who suffer from diabetes and cardiovascular disease are even more likely to have complications or die.
According to many references, heart rate variability (HRV) is a way to estimate the activity of the autonomic nervous system. Since the sympathetic nervous system and parasympathetic nervous system mutually affect the low-frequency part of the heart rate, while the parasympathetic nervous system alone controls the high- frequency part, the most common way to analyze heart rate variability is to use power spectrum density to get the power ratio (LF/HF) between heartbeats and speculate about how much the cardiovascular system is controlled by the autonomic nervous system.
This study aims at the safety of anesthetic in operations, combining relevant, non- intrusive measuring devices : electrocardiograms and photoplethysmographic. The thesis also analyzes the changes of HRV and pulse wave transit time (PTT) during anesthesia by LabVIEW8.6 based application program to estimate the patients’ autonomic nervous system and cardiovascular system. Eventually, the method of assessment to offer doctors a reference during an operation was build so that the patients could recover in the shortest time by giving them the appropriate anesthetic dosage.
Subjects
anesthesia
barbiturates
vascular compliance
electrocardiogram
photoplethysmographic
pulse wave transit time
heart rate variability
SDGs
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