INTEGRATED MICROFLUIDIC CHIP FOR AUTOMATED AND CONTINUOUS PHAGE SELECTION
Journal
MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ISBN
9781733419048
Date Issued
2022-01-01
Author(s)
Abstract
Selecting specific antibodies of the cell from the phage display library is essential for targeted therapy. However, traditional methods require heavily manual operation and involve complicated devices. To tackle these limitations, we developed a low-cost microfluidic device which was integrated with fluidic manipulation components to promote panning efficiency. This method allows us to reduce the reaction time between phage selection cycles with automatic operation and shows the potential to replace the traditional panning method.
Subjects
Microfluidic Chip | Phage-Display | Whole Cell Panning
Type
conference paper