Low prevalence of hepatitis C virus infection among dentists in Taiwan
Journal
Journal of Medical Virology
Journal Volume
40
Journal Issue
1
Pages
10-13
Date Issued
1993
Author(s)
Abstract
To evaluate whether hepatitis C virus (HCV) infection is an occupational hazard in the dental environment, serum samples collected in 1990–1991 from 461 dentists were tested for the antibody to HCV (anti?HCV) with first? and second?generation HCV enzyme?linked immunoassays (EIAs). Five of the 363 (1.38%) serum samples were reactive by the first?generation (C100–3) HCV EIA. Of the same 363 samples and the other 98 samples, 3 (0.65%) were reactive by the second?generation EIA. Those samples positive by the first? and/or second?generation HCV EIA were analyzed further by cDNA/polymerase chain reaction (PCR) to detect the presence of HCV RNA. Only 1 of the 5 first?generation EIA reactive samples were PCR positive. These results are comparable to the anti?HCV prevalence of healthy blood donors (0.95% by C100–3 assay) and pregnant women (0.63% by recombinant immunoblot assay). We conclude that the prevalence of HCV infection among dentists in Taiwan is low, and there is no increased risk of HCV infection through the practice of dentistry, at least in our area. ? 1993 Wiley?Liss, Inc. Copyright ? 1993 Wiley?Liss, Inc., A Wiley Company
SDGs
Other Subjects
adult; article; controlled study; dentist; hepatitis c; hepatitis c virus; human; infection risk; occupational exposure; priority journal; taiwan; Adult; Dentists; False Negative Reactions; Hepacivirus; Hepatitis Antibodies; Hepatitis C; Hepatitis C Antibodies; Human; Immunoenzyme Techniques; Occupational Diseases; Occupational Exposure; Polymerase Chain Reaction; Prevalence; RNA, Viral; Support, Non-U.S. Gov't; Taiwan
Type
journal article