The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria
Journal
Allergy
Journal Volume
81
Journal Issue
8
Start Page
2582-2632
ISSN
0105-4538
1398-9995
Date Issued
2026-02-06
Author(s)
Zuberbier, Torsten
Ansari, Zainab AbdulHameed
Abdul Latiff, Amir H.
Abuzakouk, M. M.
Agcaoili‐De Jesus, Maria Socorro
Agondi, Rosana C.
Al‐Ahmad, Mona
Alangari, Abdullah A.
Alhameli, H.
Alonso Bello, Cesar D.
Alshareef, Saad
Al‐Tamemi, Salem
Altrichter, Sabine
Al Wahshi, Humaid
Aquilina, S.
Araújo, M.
Arnaout, Rand
Asero, Riccardo
Ballmer‐Weber, Barbara
Bangert, Christine
Bauer, Andrea
Ben‐Shoshan, Moshe
Bernstein, Jonathan A.
Bindslev‐Jensen, Carsten
Bizjak, Mojca
Boccon‐Gibod, Isabelle
Bonnekoh, Hanna
Bouillet, Laurence
Brockow, Knut
Brzoza, Zenon
Bulatović Ćalasan, M.
Bulkhi, Adeeb
Buttgereit, Thomas
Bygum, Anette
Caballero, Teresa
Calderon, Oscar
Campos, R.
Cancian, Mauro
Carne, Emily
Castor, Mary Anne
Cerecedo, Inmaculada
Çetinarslan, T.
Cherrez‐Ojeda, Ivan
Chkhikvadze, N.
Chong‐Neto, Herberto J.
Choo, Karen
Christoff, George
Ciupka, K.
Conlon, Niall
Costa, Célia
Craig, Timothy J
Criado, Paulo
Danilycheva, Inna
Darlenski, Razvigor
De Arruda Chaves, Erika
de Montjoye, Laurence
Doutre, M.‐S.
Du‐Thanh, Aurelie
Ebo, Didier
Elkhalifa, S.
Elmariah, S.
El‐Shanawany, Tariq
Ensina, Luis F.
Ertaş, Ragip
Fachini Jardim Criado, Roberta
Ferrer, Marta
Ferrucci, Silvia
Fok, Jie Shen
Fomina, Daria
Fonacier, Luz
Fouda, Ghada
Francescantonio, I.
Fukunaga, Atsushi
Galvan Calle, César A.
Garcia, Elizabeth
Gáspár, Krisztian
Gelincik, Aslı
Geng, Songmei
Godse, Kiran
Gonçalo, Margarida
Gotua, Maia
Grattan, C.
Grosber, Martine
Guidos Fogelbach, Guillermo
Guilarte, Mar
Guillod, R.
Hamelmann, Eckard
Hawkes, Jason
Hayama, Koremasa
Heuer, Ruben
Hide, Michihiro
Hoetzenecker, Wolfram
Inomata, Naoko
Kang, Hye‐Ryun
Kaplan, Allen P.
Kapp, Alexander
Karam, M.
Kasperska‐Zajac, Alicja
Katelaris, Constance H.
Kessel, Aharon
Khoshkhui, Maryam
Kim, Brian
Kinaciyan, Tamar
Kocatürk, Emek
Kolacinska‐Flont, Marta
Kolkhir, Pavel
Konstantinou, George N.
Kosnik, Mitja
Krasowska, Dorota
Kulthanan, Kanokvalai
Kumaran, Muthu S.
Kuprys‐Lipinska, Izabela
Labrador, Moisés
Larco, Jose Ignacio
Larenas‐Linnemann, Désirée
Latysheva, Elena
Lazaridou, E.
Li, Philip H.
Lima, H.
Lippert, Undine
Magerl, Markus
Makris, Michael
Alves Marcelino, João
Marzano, Angelo V.
Medina, Iris
Meshkova, Raisa
Micallef, D.
Mohammed Ali, Ramzy
Mortz, Charlotte G.
Munoz, Melba
Oude Elberink, Hanneke N. G.
Nakonechna, Alla
Nasr, Iman
Nast, Alexander
Netchiporouk, Elena
Nettis, Eustachio
Nieto, Sandra
Ogueta Canales, Isabel
Okas, T.‐L.
Orfali, Raquel L.
Özkaya, Esen
Parisi, Claudio
Pennitz, A.
Pawankar, Ruby
Pereira, Manuel P.
Peter, Jonny
Petkova, Elena
Pigatto, P. D.
Podder, Indrashis
Popov, T.
Porebski, Grzegorz
Pyatilova, Polina
Ramon, German D.
Ratti Sisa, Hector A.
Recto, Marysia Stella
Ress, Krista
Ridge, Katie
Riedl, Marc
Ritchie, Carla
Rosario Filho, Nelson
Rosmaninho, Isabel
Rudenko, Michael
Rukhadze, Maia
Rutkowski, Krzysztof
Sabato, Vito
Sahiner, Umit M.
Saini, Sarbjit
Saleh Al Sabbagh, F.
Salman, Andac
Salvo, Fulvio
Sanchez, Jorge
Santucci, A.
Schliemann, Sibylle
Schmid‐Grendelmeier, Peter
Sekerel, Bulent E.
Serpa, Faradiba
Sheikh, Farrukh
Sheikh, J.
Shendi, H.
Siebenhaar, Frank
Sonomjamts, M.
Soria, Angele
Sousa Pinto, Bernardo
Staevska, Maria
Staubach, Petra
Stephan, M.
Stevanovic, Katarina
Stingeni, Luca
Stobiecki, Marcin
Su Küçük, Özlem
Sussman, Gordon
Szegedi, Andrea
Takahagi, Shunsuke
Tanaka, Akio
Teovska Mitrevska, Natasa
Thomsen, Simon Francis
Toubi, Elias
Tsatsou, Fragkiski
Turk, Murat
Vadasz, Zahava
Valerieva, Anna
Valle, Solange
Doorn, Martijn van
Veleiro Perez, Beatriz
Vera Ayala, Carolina E.
Vestergaard, Christian
Vieira, Rafael J.
Maruta, C. W.
Wedi, Bettina
Werner, Ricardo N.
Yap, Evelyn Wen Yee
Xepapadaki, Paraskevi
Xiang, Yi‐Kui
Ye, Young‐Min
Yong, Patrick
Yosipovitch, Gil
Zalewska‐Janowska, Anna
Zeyen, Christoph
Zhao, Zuotao
Metz, Martin
Giménez‐Arnau, Ana M.
Abstract
This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), with the participation of 210 delegates from 107 national and international societies, from 59 countries. The consensus conference was held on December 6th, 2024. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell-driven disease, defined by a rapid appearance of wheals, angioedema, or both. The lifetime prevalence of acute urticaria is estimated to be approximately 20%. Chronic urticaria, categorized as either chronic spontaneous urticaria or chronic inducible urticaria, is disabling, impairs quality of life, and affects performance at work and school, however, novel therapies are available. This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.
Subjects
angioedema
consensus
evidence‐based
hives
itch
mast cell
urticaria
wheals
Publisher
Wiley
Type
journal article