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Cytotoxic Pregnane Steroids from the Formosan Soft Coral Stereonephthya crystalliana
Resource
Journal of Natural Products 69 (1): 103-106
Journal
Journal of Natural Products
Journal Volume
69
Journal Issue
1
Pages
103-106
Date Issued
2006
Date
2006
Author(s)
Abstract
Nine new steroids, stereonsteroids A-I (1-9), were isolated from the methylene chloride solubles of the Formosan soft coral Stereonephthya crystalliana K?kenthal. The structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro. ? 2006 American Chemical Society and American Society of Pharmacognosy.
SDGs
Other Subjects
cytotoxic agent; dichloromethane; pregnane derivative; stereonsteroid; stereonsteroid A; stereonsteroid B; stereonsteroid C; stereonsteroid D; stereonsteroid E; stereonsteroid F; stereonsteroid G; stereonsteroid H; stereonsteroid I; steroid; unclassified drug; article; bioassay; cancer cell culture; carbon nuclear magnetic resonance; cell strain HT29; controlled study; coral; drug cytotoxicity; drug isolation; human; human cell; in vitro study; mass spectrometry; nuclear Overhauser effect; proton nuclear magnetic resonance; Stereonephthya crystalliana; structure analysis; Animals; Anthozoa; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pregnanes; Steroids; Taiwan; Tumor Cells, Cultured; Alcyonacea; Anthozoa
Type
journal article
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Format
Adobe PDF
Checksum
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