MicroRNA in lung cancer
Journal
British Journal of Cancer
Journal Volume
103
Journal Issue
8
Pages
1144-1148
Date Issued
2010
Author(s)
Abstract
MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction. ? 2010 Cancer Research UK.
SDGs
Other Subjects
biological marker; microRNA; antineoplastic agent; microRNA; cancer risk; gene control; lung cancer; lung carcinogenesis; outcome assessment; priority journal; risk assessment; short survey; animal; biological model; biosynthesis; Carcinoma, Non-Small-Cell Lung; drug delivery system; genetics; human; Lung Neoplasms; pathology; physiology; procedures; prognosis; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Delivery Systems; Humans; Lung Neoplasms; MicroRNAs; Models, Biological; Prognosis; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Drug Delivery Systems; Humans; Lung Neoplasms; MicroRNAs; Models, Biological; Prognosis
Type
journal article