Synthesis and Research of Thermosensitive Magnetic Latex Particle

In our study, we discuss the copolymer of NIPAAM (N-isopropylacrylamide) and AA (acrylic acid) in different ratio of AA/NIPAAM and in different concentration of crosslinking agent. We test this copolymer in some experiments incluiding TEM, LCST, drug release and protein (BSA) bonding.

Then synthesizing the magnetic hydrogel, we use different method to synthesize “iron oxide/polymer” form the traditional method. In our work, we firstly synthesize the hydrogel. Second, using the functional group(-COOH) on the hyrogel surface to bond with Fe2+ and Fe3+. Finally, we put ammonia into the latex, and we can get magnetic hydrogel.

According to each test about poly(NIPAAM-co-AA), we choose suitable group to synthesize magnetic hydrogel. Then we test all events described in the first paragraph. From all testing experiments, we can realize the properties of the (magnetic) hydrogel and the effect on experimental results from each parameter.