Radiosensitization in Cancer Treatment with Gold nanoparticles through Synergistic Sonoporation
Journal
IEEE International Ultrasonics Symposium, IUS
Journal Volume
2019-October
Pages
1536-1538
Date Issued
2019
Author(s)
Abstract
We demonstrated synergistic radiosensitization in human liver cancer using gold nanoparticle-encapsulated microbubbles (AuMB) and ultrasound. Microbubbles-mediated sonoporation enhanced cellular uptake of gold nanoparticles (AuNP). Higher cavitation signals were associated with more DNA damages and inferior cancer cell survivals after mega-voltage (MV) X-ray irradiation. ? 2019 IEEE.
SDGs
Other Subjects
Cavitation; Diseases; Fiber optic sensors; Metal nanoparticles; Cancer cells; Cellular uptake; DNA damages; Human liver; Microbubbles; Radio-sensitization; Sonoporation; X ray irradiation; Gold nanoparticles
Publisher
IEEE Computer Society
Type
conference paper