Intrauterine exposure to per- and polyfluoroalkyl substances may harm children's lung function development
Journal
Environmental research
Journal Volume
192
Date Issued
2021
Author(s)
Abstract
Per- and polyfluoroalkyl substances (PFAS), such as perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA) and perfluoroundecanoic acid (PFUA), are common persistent environmental organic pollutants. Animal studies have indicated that PFAS influence inflammatory responses and lung development. However, whether prenatal or childhood PFAS exposure affects children's lung function remains unclear. This study aimed to investigate both in utero exposure and childhood exposure to PFAS and the relationships between them and lung function development in childhood.
Subjects
Allergic disease; Lung development; Lung function; Prenatal exposure; per- and polyfluoroalkyl substances
Other Subjects
perfluorononanoic acid; perfluorooctanesulfonic acid; perfluorooctanoic acid; perfluoroundecanoic acid; alkanesulfonic acid; fluorocarbon; bioaccumulation; blood; child health; concentration (composition); immune response; organic pollutant; plasma; pollu
Type
journal article